Publications

A comparative study of click handle stability in common ligation conditions

Fawcett Caitlin, Watson Joe, Richards Stephen, Doherty Alfred E, Seki Hikaru, Love Elizabeth A, Coles Charlotte H, Coe Diane M, Jamieson Craig

Bioconjugate Chemistry (2025)

https://doi.org/10.1021/acs.bioconjchem.5c00095

eAmidation : an electrochemical amidation of aldehydes via the oxidation of N-aryl hydrazones

Chen Luke, Thompson James DF, Jamieson Craig

Advanced Synthesis and Catalysis (2025)

https://doi.org/10.1002/adsc.202500037

The androgen receptor amino-terminal domain : structure, function and therapeutic potential

Hunter Irene, Jamieson Craig, McEwan Iain

Endocrine Oncology Vol 5 (2025)

https://doi.org/10.1530/EO-24-0061

Ion mobility mass spectrometry unveils conformational effects of drug lead EPI-001 on the intrinsically disordered N-terminal domain of the Androgen Receptor

Ahmed Ikhlas M M, Rofe Adam, Henry Martyn C, West Eric, Jamieson Craig, McEwan Iain J, Beveridge Rebecca

Protein Science Vol 34 (2025)

https://doi.org/10.1002/pro.5254

An electrosynthesis of 1,3,4-oxadiazoles from N-acyl hydrazones

Chen Luke, Thompson James D F, Jamieson Craig

Chemistry - A European Journal Vol 30 (2024)

https://doi.org/10.1002/chem.202403128

A framework for the biophysical screening of antibody mutations targeting solvent-accessible hydrophobic and electrostatic patches for enhanced viscosity profiles

Armstrong Georgina B, Shah Vidhi, Sanches Paula, Patel Mitul, Casey Ricky, Jamieson Craig, Burley Glenn A, Lewis William, Rattray Zahra

Computational and Structural Biotechnology Journal Vol 23, pp. 2345-2357 (2024)

https://doi.org/10.1016/j.csbj.2024.05.041

More publications

Research Interests

Biography

Craig Jamieson earned his BSc (Hons) in Chemistry at the University of Glasgow in 1996. His PhD studies were carried out under the direction of Professor R Ramage at the University of Edinburgh (1999).  Following postdoctoral research under the supervision of Professor S V Ley at the University of Cambridge, in 2001 he was appointed as a Principal Scientist in GlaxoSmithKline's Discovery Medicinal Chemistry group working on a range of exploratory medicinal chemistry programmes.  In 2004, Craig joined Organon Laboratories (later Merck Research Labs) as a Group Leader in the Medicinal Chemistry Department, with responsibility for hit to clincal candidate optimisation.  In August 2010, Craig was appointed as a John Anderson Research Lecturer in Chemical Biology, based in the Department of Pure and Applied Chemistry at the University of Strathclyde where he is currently a Professor in the Chemical Biology and Medicinal Chemistry Research Theme.

Research Interests

A major area of focus for our research continues to be in the Chemistry-Biology-Medicine continuum.  In this regard, we have a number of active programmes centred around hit and lead identification on disease targets and mechanisms in areas of significant societal need.  Allied to our work in the medicinal chemistry sphere, we also have a keen interest in the development of novel, enabling synthetic methodologies to enhance the armamentarium of molecule makers working in our arena.  We collaborate with groups and industrial partners locally, nationally and globally in order to effectively meet our research goals.

Professional Activities

Sequence engineering to improve syringeability of high concentration mAb formulations

Contributor

23/11/2022

Gyros Protein Technologies

Visiting researcher

1/6/2019

Almac Sciences

Visiting researcher

31/5/2019

Aldeyra Therapeutics Inc

Consultant

1/10/2018

Arc Scientific

Consultant

1/1/2016

Syngenta Limited

Visiting researcher

1/1/2014

More professional activities

Projects

AR-NTD Inhibitors as a Novel Treatment Modalityfor Castrate Resistant Prostate Cancer

Jamieson, Craig (Principal Investigator)

01-Jan-2025 - 30-Jan-2026

Industrial Case Account - University of Strathclyde 2023 | Reid, Andrew

Jamieson, Craig (Principal Investigator) Kerr, William (Co-investigator) Reid, Andrew (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

Industrial CASE Account - University of Strathclyde 2024 | O'Brien, Megan

Jamieson, Craig (Principal Investigator) Chow, Shiao (Co-investigator) O'Brien, Megan (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

DTP 2224 University of Strathclyde | Schmid, Simon Paul

Jamieson, Craig (Principal Investigator) Murphy, John (Co-investigator) Schmid, Simon Paul (Research Co-investigator)

01-Jan-2024 - 01-Jan-2028

GLAS-CYTO: AN INTEGRATED FACILITY FOR THE BIOPHYSICAL ANALYSIS OF CELLULAR INTERACTIONS

Burley, Glenn (Principal Investigator) Chamberlain, Luke (Co-investigator) Chow, Shiao (Co-investigator) Corrigan, Damion (Co-investigator) Cunningham, Margaret Rose (Co-investigator) Faulds, Karen (Co-investigator) Jamieson, Craig (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator) Taladriz Sender, Andrea (Research Co-investigator)

01-Jan-2024 - 31-Jan-2025

A Prosperity Partnership for the Design of Next-Generation Antibody Drug Bioconjugates (Next-Gen ADC)

Burley, Glenn (Principal Investigator) Jamieson, Craig (Co-investigator) Kerr, William (Co-investigator) Nordon, Alison (Co-investigator) Rattray, Zahra (Co-investigator) Tomkinson, Nick (Co-investigator)

15-Jan-2023 - 14-Jan-2028

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